Wednesday, February 20, 2008

Mesothelioma

Interviews with people who have the disease.

Tuesday, February 19, 2008

Treatments and Clinical Trials for Mesothelioma

For years, chemotherapy has been used as treatment for mesothelioma to shrink tumors. More recently, doctors have used surgery in combination with chemotherapy with more success.

In addition, newer chemotherapy drugs in combination with surgery has increased survival rates of mesothelioma patients.

Radiation has been used to control cancer symptoms such as pain, but it is not a primary treatment for mesothelioma. It is also used in combination with other treatments for mesothelioma and may possibly assist in killing cancer cells after surgery to prevent further growth of cancer cells in the chest area.

Much more research is required to improve treatment options through clinical trials. Clinical trials are used to evaluate new cancer treatments and their effectiveness. They are an important aspect of improving treatments and the ultimate prognosis of cancer patients.

Mesothelioma patients who participate in clinical trials are able to receive new treatments before they are available to other patients.

Read more here.



Treatment for Mesothelioma

Mesothelioma is a kind of permanent cancer disease. Mesothelioma cancer occurs when tissues of our lungs or abdominal components get affected. In more cases asbestos exposure was identified as the reason for mesothelioma disease. Symptoms of mesothelioma may not appear immediately after it’s exposure, it takes time between twenty to thirty years. This enables the disease identification process a critical one.

Treatments for mesothelioma depends on the stage of the cancer, the specific part being affected, the total amount of space being affected, how long one have the problem, the look of the cancer cells under microscope and the age factor of the patient. These are the factors that are being considered before choosing the treatment option.

Treatments for mesothelioma include Surgery, Chemotherapy and Radiation Therapy.

Surgery: There are two types of surgeries available one is aggressive surgery and another one is called palliative procedures.

Aggressive surgery is done through a procedure named extra pleural pneumonectomy, by which the pleura, the lung, the diaphragm and the pericardium are removed. The aggressive surgery’s motive is to remove as much mesothelioma tumor as possible.

Palliative procedures will be done when the mesothelioma disease is at the matured stage. The motive of this procedure is to give relief to the patient from the symptoms.

Chemotherapy: In chemotherapy drugs are being used to treat mesothelioma cancer. The drugs may be in the form of pills or injections. To improve the results of chemotherapy some drugs may be used as mix in some proportion and this has given a good improvement in the treatment results.

Radiation therapy: Radiation therapy uses radiations to kill mesothelioma tumor. This procedure is complex to undergo as the tumors are surrounded by sensitive parts of our body. There are possibilities that the heart and lungs being damaged by the radiation. Lower dose radiation is one solution to slightly overcome from this critical issue.

Though mesothelioma is a permanent cancer disease and the survival rate is very low, timely identification and perfect treatment at the right time could able to help us survive some long time.

Chris Jack is the CEO of Mesothelioma Infobase. To have more information about mesothelioma and mesothelioma treatments visit Mesothelioma Infobase.

Article source here.

Mesothelioma - The 3 Main Types

In general, mesothelioma is a rare form of cancer. Different types of mesothelioma are distinguished between by where the cancer is growing. Pleural mesothelioma, the most common, accounting for 75% of all mesothelioma cases, is where cancerous cells develop on the lining of the lungs. The next most common form of mesothelioma is peritoneal mesothelioma and this is where cancerous cells grow on the peritoneum which is the lining of the abdomen. Pericardial mesothelioma, the least common major form of mesothelioma, makes up roughly 5% of all mesothelioma cases. This is where malignant cancer cells grow on the lining of the heart.

All three of these forms of mesothelioma are caused by asbestos. Asbestos is a naturally occurring fibrous mineral that was discovered around the 1860s. Due to its highly useful property of being fireproof, asbestos was used greatly in construction in the 1920s, 1930s and 1940s. It was not until the early 1960s when the severe health hazards that asbestos causes were discovered, that asbestos stopped being used. When exposed to asbestos with insufficient protection a person will breathe in tiny asbestos fibres which are suspended in the air. These fibres pass into the respiratory system until they become lodged in the lining of the lungs. Over time, an accumulation of these asbestos fibres in the lungs can cause pleural mesothelioma. Asbestos fibres may also pass into the lymphatic system and be transported to either the lining of the abdomen or the tissue surrounding the heart. This may cause either peritoneal mesothelioma or pericardial mesothelioma.

In terms of symptoms, the three main types of mesothelioma have some symptoms in common with each other. These symptoms are usual of all three types: chest pain, shortness of breath, coughing, coughing up blood, vomiting, nausea, weight loss and loss of appetite. An additional symptom of pericardial mesothelioma is palpitations.

There are a few treatments for all types of mesothelioma but none of these have a high success rate. The effectiveness of the treatment depends on how early and how aggressively the cancer is treated. If the cancerous cells are treated when they have fully matured and developed then it is unlikely that treatment methods will be successful. Treatment methods include chemotherapy which is the use of drugs to kill the cancer, radiation therapy which uses a radiation dosage to kill off cancerous cells and surgery which attempts to gain long term control over the cancer by removing a large portion of malignant cells. These treatment methods can be combined in the form of dual therapy.

For more information on pericardial mesothelioma such as the risks, causes, symptoms and treatments go to:

http://www.pericardialmesothelioma.co.uk
http://www.pericardial-mesothelioma.co.uk
http://www.asbestos-resource.co.uk

Article source here.

What Radical Mesothelioma Treatments Are Available?

Current radical mesothelioma treatments include chemotherapy treatments, radiation treatments, surgical treatments and experimental therapies and drugs. Research news reports the limited success of present treatments for Mesothelioma.

Mesothelioma research news indicates that traditional treatments viz. single or multi-drug chemotherapy has a response rate of about 20%. Radiation treatments, usually used in conjunction with surgery or chemotherapy treatments can relieve pain and shrink tumors, making breathing easier. However, radiation treatments can also cause severe side effects.

Efforts To Combat Mesothelioma

Mesothelioma can take between ten and sixty years to develop after inhalation of respirable asbestos fibers, but Mesothelioma progresses fast. Radical surgeries as mesothelioma treatments have had limited success. Surgical treatments attempted include extra-pleural pneumonectomy (EPP) and pleurectomy.

Treatment news indicates that in EPP over 15% patients die soon after surgery. EPP involves removal of pleura, diaphragm, pericardium, part of the phrenic nerve and the entire tumor-affected lung and has to be supported by chemotherapy or radiation.

The pleurectomy treatments involve removal of the pleura without removing the whole lung. These treatments are best in patients with good lung expansion who tend to accumulate fluid. In combination with radiation pleurectomy is reported in treatment news to have given 22-month survival in 50% and 24-month survival in 41% cases in a 27-patient group with mesothelioma of the epithelial subtype.

Surgical treatments of mesothelioma have not been shown to offer significant advantages over the limited non-surgical treatments. Experimental drugs under evaluation include treatments by Onconase, Lovastatin and an Endostatin and angiostatin combination.

The Mesothelioma Research Foundation of America is funding research on mesothelioma cure. The USC Norris Comprehensive Cancer Center in Los Angeles has completed Phase I Clinical Trials on a new mesothelioma treatment drug called Veglin.

Phase II Clinical trials of Veglin have begun in July 2004, opening exciting treatment possibilities for mesothelioma victims.

Jon Butt publishes http://www.the-mesothelioma-guide.com With the web being packed with mis-information http://www.the-mesothelioma-guide.com is a leading free resource of Mesothelioma support, advice and legal help along with alternative remedies, natural supplements and more. Helping both you and your loved ones.

Article source here.

What is Pericardial Mesothelioma?

Pericardial mesothelioma is the rarest type of the three forms of mesothelioma. It makes up less than 10% of all mesothelioma patients. Approximately 2,000 new cases of mesothelioma are diagnosed each year, but fewer than 200 of them are pericardial. As with the other mesotheliomas, it is caused by exposure to asbestos. This type affects the pericardium, the protective sac that covers the heart and provides lubrication so that it can beat properly. Because it is so rare, there is little specific research on this disease, and it is still not clearly understood how the asbestos fibers become lodged in the pericardium.

Symptoms of pericardial mesothelioma are similar to other forms of mesothelioma, although its rarity has made it difficult for specialists to determine a specific set of common symptoms. Heart palpitations are more common with this form of mesothelioma than with the others. Additionally, patients may experience difficulty breathing, fever, and cough.

Diagnosis of pericardial mesothelioma is problematic, as the nature of its symptoms is relatively non-specific, in that they can appear as a result of several other cardiac conditions. Unfortunately for most patients, by the time symptoms of the disease appear, the cancer has progressed to a stage where conventional treatments are largely ineffective for anything other than providing temporary relief of symptoms.

As a direct consequence of the difficulties in definitively diagnosing pericardial mesothelioma, and the fact that it is usually only minimally symptomatic until its advanced stages, the prognosis for patients is very poor, with a mean survival time of only six months following diagnosis.

Article source here.

Mesothelioma pictures